Just an FYI, (since I don't feel like quoting), David was taken out in the Dark Forest, NOT the Quicksand Bog. And David and Karisa had the "Enormous Feather" layout, not the "Discarded Seal" layout. Just saying.
As for the Mystical Spellbook run, Katie definitely should have gone in first. She was way faster than Jared and she would have been impressive in the temple. Also, notice how the Chamber door opened during the run? That had to have been where the other guard was. And if Katie had encountered that guard and got taken out in the Ancient Warriors, Jared would have gone in and.... who knows what would have happened?
Oops, I was probably the one that said that David was taken out in the Quicksand Bog. I guess Karisa's stupidity there blanked my memory about the run before she entered.

And we were comparing the "Me Linh" run to the "Ivan the Terrible" run, so I don't think anyone said that Karisa and David had the "Ivan the Terrible" layout.

And I agree, the team wouldn't have won if Katie was taken out early in the Chamber. But assuming she continued on Jared's path, she would've been taken out in the Quicksand Bog with over a minute left on the clock. That should've been enough time for Jared to reach the Mystical Spellbook and bring it out. Or if Jared was taken out in the Chamber first, then Katie may have had enough time to bring the artifact out for the win. At least Jared was competent for the most part though. Its not like he was like Lissy or Janeen who would've had no chance in winning if Nate and Jay went in first for their run.
Here's another run no one really talks about - "The Helmet of Joan of Arc". In this run, the team made it pretty far with a lengthy layout. But what hurt them was that Mandy found the key in the Tomb of the Ancient Kings but did not use it. Instead, she used the slow Well bucket. Plus, she was kind of slow. My thoughts would be that if Mandy went in first and Eddie went in second, then I think this team would've won. Mandy would've been taken out in the Room of Harmonic Convergence and Eddie was fast and hopefully would've taken the Tomb-Shrine shortcut.